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Shigella IpaH9.8 limits GBP1-dependent LPS release from intracytosolic bacteria to suppress caspase-4 activation

Pyroptosis is an inflammatory form of cell death induced upon recognition of invading microbes. During an infection, pyroptosis is enhanced in interferon-gamma-exposed cells via the actions of members of the guanylate-binding protein (GBP) family. GBPs promote caspase-4 (CASP4) activation by enhanci...

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Detalles Bibliográficos
Autores principales:	Goers, Lisa, Kim, Kyungsub, Stedman, Teagan C., Canning, Patrick J., Mou, Xiangyu, Ernst, Nadja Heinz, Coers, Jörn, Lesser, Cammie F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104580/ https://www.ncbi.nlm.nih.gov/pubmed/37014865 http://dx.doi.org/10.1073/pnas.2218469120

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