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Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain

For transcription initiation, RNA polymerase II (Pol II) forms a preinitiation complex (PIC) that associates with the general coactivator Mediator. Whereas atomic models of the human PIC-Mediator structure have been reported, structures for its yeast counterpart remain incomplete. Here, we present a...

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Detalles Bibliográficos
Autores principales: Schilbach, Sandra, Wang, Haibo, Dienemann, Christian, Cramer, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104585/
https://www.ncbi.nlm.nih.gov/pubmed/37014863
http://dx.doi.org/10.1073/pnas.2220542120