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Structural basis of calmodulin modulation of the rod cyclic nucleotide-gated channel

Calmodulin (CaM) regulates many ion channels to control calcium entry into cells, and mutations that alter this interaction are linked to fatal diseases. The structural basis of CaM regulation remains largely unexplored. In retinal photoreceptors, CaM binds to the CNGB subunit of cyclic nucleotide-g...

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Detalles Bibliográficos
Autores principales: Barret, Diane C. A., Schuster, Dina, Rodrigues, Matthew J., Leitner, Alexander, Picotti, Paola, Schertler, Gebhard F. X., Kaupp, U. Benjamin, Korkhov, Volodymyr M., Marino, Jacopo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104587/
https://www.ncbi.nlm.nih.gov/pubmed/37011209
http://dx.doi.org/10.1073/pnas.2300309120