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Structural basis of calmodulin modulation of the rod cyclic nucleotide-gated channel
Calmodulin (CaM) regulates many ion channels to control calcium entry into cells, and mutations that alter this interaction are linked to fatal diseases. The structural basis of CaM regulation remains largely unexplored. In retinal photoreceptors, CaM binds to the CNGB subunit of cyclic nucleotide-g...
Autores principales: | Barret, Diane C. A., Schuster, Dina, Rodrigues, Matthew J., Leitner, Alexander, Picotti, Paola, Schertler, Gebhard F. X., Kaupp, U. Benjamin, Korkhov, Volodymyr M., Marino, Jacopo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104587/ https://www.ncbi.nlm.nih.gov/pubmed/37011209 http://dx.doi.org/10.1073/pnas.2300309120 |
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