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Loss of RPA1 Impairs Peripheral T Cell Homeostasis and Exacerbates Inflammatory Damage through Triggering T Cell Necroptosis (Adv. Sci. 11/2023)

T Cell homeostasis The article number 2206344 by Yuxin Yin, Xuehui Zhang, Xuliang Deng, Dan Lu, and co‐workers uncovers that peripheral T cells can undergo necroptosis instead of apoptosis when endogenous RPA1 is deleted, which leads to severe lymphopenia and increases the susceptibility of autoinfl...

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Detalles Bibliográficos
Autores principales: Song, Jia, Zhang, Xin, Yin, Yue, Guo, Mengfan, Zhao, Xuyang, Wang, Likun, Ren, Caixia, Yin, Yuxin, Zhang, Xuehui, Deng, Xuliang, Lu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104623/
http://dx.doi.org/10.1002/advs.202370061