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Cholesterol‐Amino‐Phosphate (CAP) Derived Lipid Nanoparticles for Delivery of Self‐Amplifying RNA and Restoration of Spermatogenesis in Infertile Mice

Male infertility caused by genetic mutations is an important type of infertility. Currently, there is no reliable method in the clinic to address this medical need. The emergence of mRNA therapy provides a possible strategy for restoring mutant genes in the reproductive system. However, effective de...

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Detalles Bibliográficos
Autores principales: Du, Shi, Li, Wenqing, Zhang, Yuebao, Xue, Yonger, Hou, Xucheng, Yan, Jingyue, Cheng, Jeffrey, Deng, Binbin, McComb, David W., Lin, Jennifer, Zeng, Hong, Cheng, Xiaolin, Irvine, Darrell J., Weiss, Ron, Dong, Yizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104632/
https://www.ncbi.nlm.nih.gov/pubmed/36748274
http://dx.doi.org/10.1002/advs.202300188