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Cholesterol‐Amino‐Phosphate (CAP) Derived Lipid Nanoparticles for Delivery of Self‐Amplifying RNA and Restoration of Spermatogenesis in Infertile Mice
Male infertility caused by genetic mutations is an important type of infertility. Currently, there is no reliable method in the clinic to address this medical need. The emergence of mRNA therapy provides a possible strategy for restoring mutant genes in the reproductive system. However, effective de...
Autores principales: | Du, Shi, Li, Wenqing, Zhang, Yuebao, Xue, Yonger, Hou, Xucheng, Yan, Jingyue, Cheng, Jeffrey, Deng, Binbin, McComb, David W., Lin, Jennifer, Zeng, Hong, Cheng, Xiaolin, Irvine, Darrell J., Weiss, Ron, Dong, Yizhou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104632/ https://www.ncbi.nlm.nih.gov/pubmed/36748274 http://dx.doi.org/10.1002/advs.202300188 |
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