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Phosphorylation of USP29 by CDK1 Governs TWIST1 Stability and Oncogenic Functions

Triple‐negative breast cancer (TNBC) is a highly lethal malignancy with limited therapy options. TWIST1, a key transcriptional factor of epithelial‐mesenchymal transition (EMT), contributes to self‐renewal of cancer stem‐like cells (CSCs), chemo‐resistance, metastasis, and TNBC‐related death. Howeve...

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Detalles Bibliográficos
Autores principales: Guan, Tangming, Li, Mei, Song, Yan, Chen, Jiayi, Tang, Jiaxin, Zhang, Caishi, Wen, Yalei, Yang, Xiao, Huang, Lei, Zhu, Yingjie, Wang, Hongxian, Ding, Ke, Zheng, Junxia, Zhang, Haoxing, Liu, Tongzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104637/
https://www.ncbi.nlm.nih.gov/pubmed/36782089
http://dx.doi.org/10.1002/advs.202205873