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Expanded Potential Stem Cells from Human Embryos Have an Open Chromatin Configuration with Enhanced Trophoblast Differentiation Ability

Human expanded potential stem cells (hEPSC) have been derived from human embryonic stem cells and induced pluripotent stem cells. Here direct derivation of hEPSC from human pre‐implantation embryos is reported. Like the reported hEPSC, the embryo‐derived hEPSC (hEPSC‐em) exhibit a transcriptome simi...

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Detalles Bibliográficos
Autores principales: Chen, Andy Chun Hang, Lee, Yin Lau, Ruan, Hanzhang, Huang, Wen, Fong, Sze Wan, Tian, Siyu, Lee, Kai Chuen, Wu, Genie Minju, Tan, Yongqi, Wong, Timothy Chun Hin, Wu, Jian, Zhang, Weiyu, Cao, Dandan, Chow, Judy Fung Cheung, Liu, Pengtao, Yeung, William Shu Biu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104645/
https://www.ncbi.nlm.nih.gov/pubmed/36775869
http://dx.doi.org/10.1002/advs.202204797