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Dock-able linear and homodetic di, tri, tetra and pentapeptide library from canonical amino acids: SARS-CoV-2 Mpro as a case study

Peptide-based therapeutics are increasingly pushing to the forefront of biomedicine with their promise of high specificity and low toxicity. Although noncanonical residues can always be used, employing only the natural 20 residues restricts the chemical space to a finite dimension allowing for compr...

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Detalles Bibliográficos
Autores principales: Ahmad, Sarfraz, Mirza, Muhammad Usman, Trant, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104786/
https://www.ncbi.nlm.nih.gov/pubmed/37275125
http://dx.doi.org/10.1016/j.jpha.2023.04.008