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Dock-able linear and homodetic di, tri, tetra and pentapeptide library from canonical amino acids: SARS-CoV-2 Mpro as a case study
Peptide-based therapeutics are increasingly pushing to the forefront of biomedicine with their promise of high specificity and low toxicity. Although noncanonical residues can always be used, employing only the natural 20 residues restricts the chemical space to a finite dimension allowing for compr...
Autores principales: | Ahmad, Sarfraz, Mirza, Muhammad Usman, Trant, John F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Xi'an Jiaotong University
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104786/ https://www.ncbi.nlm.nih.gov/pubmed/37275125 http://dx.doi.org/10.1016/j.jpha.2023.04.008 |
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