Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis

Tau tubulin kinase 1 and 2 (TTBK1/2) are highly homologous kinases that are expressed and mediate disease-relevant pathways predominantly in the brain. Distinct roles for TTBK1 and TTBK2 have been delineated. While efforts have been devoted to characterizing the impact of TTBK1 inhibition in disease...

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Detalles Bibliográficos
Autores principales: Bashore, Frances M., Marquez, Ariana B., Chaikuad, Apirat, Howell, Stefanie, Dunn, Andrea S., Beltran, Alvaro A., Smith, Jeffery L., Drewry, David H., Beltran, Adriana S., Axtman, Alison D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104807/
https://www.ncbi.nlm.nih.gov/pubmed/37059819
http://dx.doi.org/10.1038/s41598-023-32854-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104807/
https://www.ncbi.nlm.nih.gov/pubmed/37059819
http://dx.doi.org/10.1038/s41598-023-32854-4

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