Poricoic acid A suppresses renal fibroblast activation and interstitial fibrosis in UUO rats via upregulating Sirt3 and promoting β-catenin K49 deacetylation

Renal interstitial fibrosis is the common pathological process of various chronic kidney diseases to end-stage renal disease. Inhibition of fibroblast activation attenuates renal interstitial fibrosis. Our previous studies show that poricoic acid A (PAA) isolated from Poria cocos is a potent anti-fi...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Dan-Qian, Chen, Lin, Guo, Yan, Wu, Xia-Qing, Zhao, Ting-Ting, Zhao, Hai-Ling, Zhang, Hao-Jun, Yan, Mei-Hua, Zhang, Guo-Qiang, Li, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104829/
https://www.ncbi.nlm.nih.gov/pubmed/36470978
http://dx.doi.org/10.1038/s41401-022-01026-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104829/
https://www.ncbi.nlm.nih.gov/pubmed/36470978
http://dx.doi.org/10.1038/s41401-022-01026-x

Ejemplares similares