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Structural basis for sequence-specific recognition of guide and target strands by the Archaeoglobus fulgidus Argonaute protein

Argonaute (Ago) proteins are found in all three domains of life. The best-characterized group is eukaryotic Argonautes (eAgos). Being the structural core of RNA interference machinery, they use guide RNA molecules for RNA targeting. Prokaryotic Argonautes (pAgos) are more diverse, both in terms of s...

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Detalles Bibliográficos
Autores principales: Manakova, Elena, Golovinas, Edvardas, Pocevičiūtė, Reda, Sasnauskas, Giedrius, Grybauskas, Algirdas, Gražulis, Saulius, Zaremba, Mindaugas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104839/
https://www.ncbi.nlm.nih.gov/pubmed/37059709
http://dx.doi.org/10.1038/s41598-023-32600-w