Homology directed telomere clustering, ultrabright telomere formation and nuclear envelope rupture in cells lacking TRF2(B) and RAP1

Double-strand breaks (DSBs) due to genotoxic stress represent potential threats to genome stability. Dysfunctional telomeres are recognized as DSBs and are repaired by distinct DNA repair mechanisms. RAP1 and TRF2 are telomere binding proteins essential to protect telomeres from engaging in homology...

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Detalles Bibliográficos
Autores principales: Rai, Rekha, Biju, Kevin, Sun, Wenqi, Sodeinde, Tori, Al-Hiyasat, Amer, Morgan, Jaida, Ye, Xianwen, Li, Xueqing, Chen, Yong, Chang, Sandy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104862/
https://www.ncbi.nlm.nih.gov/pubmed/37059728
http://dx.doi.org/10.1038/s41467-023-37761-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104862/
https://www.ncbi.nlm.nih.gov/pubmed/37059728
http://dx.doi.org/10.1038/s41467-023-37761-w

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