Hepatocellular carcinoma cells loss lenvatinib efficacy in vitro through autophagy and hypoxia response-derived neuropilin-1 degradation

Despite pharmacological advances such as lenvatinib approval, therapeutic failure of hepatocellular carcinoma (HCC) remains a big challenge due to the complexity of its underlying molecular mechanisms. Neuropilin-1 (NRP1) is a co-receptor involved in several cellular processes associated to chemores...

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Detalles Bibliográficos
Autores principales: Fernández-Palanca, Paula, Payo-Serafín, Tania, San-Miguel, Beatriz, Méndez-Blanco, Carolina, Tuñón, María J., González-Gallego, Javier, Mauriz, José L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104874/
https://www.ncbi.nlm.nih.gov/pubmed/36376373
http://dx.doi.org/10.1038/s41401-022-01021-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104874/
https://www.ncbi.nlm.nih.gov/pubmed/36376373
http://dx.doi.org/10.1038/s41401-022-01021-2

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