Nucleotide binding halts diffusion of the eukaryotic replicative helicase during activation

The eukaryotic replicative helicase CMG centrally orchestrates the replisome and leads the way at the front of replication forks. Understanding the motion of CMG on the DNA is therefore key to our understanding of DNA replication. In vivo, CMG is assembled and activated through a cell-cycle-regulate...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramírez Montero, Daniel, Sánchez, Humberto, van Veen, Edo, van Laar, Theo, Solano, Belén, Diffley, John F. X., Dekker, Nynke H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104875/
https://www.ncbi.nlm.nih.gov/pubmed/37059705
http://dx.doi.org/10.1038/s41467-023-37093-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104875/
https://www.ncbi.nlm.nih.gov/pubmed/37059705
http://dx.doi.org/10.1038/s41467-023-37093-9

Ejemplares similares