Human IAPP is a contributor to painful diabetic peripheral neuropathy

Peripheral neuropathy is a frequent complication of type 2 diabetes mellitus (T2DM). We investigated whether human islet amyloid polypeptide (hIAPP), which forms pathogenic aggregates that damage pancreatic islet β cells in T2DM, is involved in T2DM-associated peripheral neuropathy. In vitro, hIAPP...

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Detalles Bibliográficos
Autores principales: Albariqi, Mohammed M.H., Versteeg, Sabine, Brakkee, Elisabeth M., Coert, J. Henk, Elenbaas, Barend O.W., Prado, Judith, Hack, C. Erik, Höppener, Jo W.M., Eijkelkamp, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104883/
https://www.ncbi.nlm.nih.gov/pubmed/36917177
http://dx.doi.org/10.1172/JCI156993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104883/
https://www.ncbi.nlm.nih.gov/pubmed/36917177
http://dx.doi.org/10.1172/JCI156993

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