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Human IAPP is a contributor to painful diabetic peripheral neuropathy

Peripheral neuropathy is a frequent complication of type 2 diabetes mellitus (T2DM). We investigated whether human islet amyloid polypeptide (hIAPP), which forms pathogenic aggregates that damage pancreatic islet β cells in T2DM, is involved in T2DM-associated peripheral neuropathy. In vitro, hIAPP...

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Detalles Bibliográficos
Autores principales:	Albariqi, Mohammed M.H., Versteeg, Sabine, Brakkee, Elisabeth M., Coert, J. Henk, Elenbaas, Barend O.W., Prado, Judith, Hack, C. Erik, Höppener, Jo W.M., Eijkelkamp, Niels
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104883/ https://www.ncbi.nlm.nih.gov/pubmed/36917177 http://dx.doi.org/10.1172/JCI156993

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