Hepatocyte SREBP signaling mediates clock communication within the liver

Rhythmic intraorgan communication coordinates environmental signals and the cell-intrinsic clock to maintain organ homeostasis. Hepatocyte-specific KO of core components of the molecular clock Rev-erbα and -β (Reverb-hDKO) alters cholesterol and lipid metabolism in hepatocytes as well as rhythmic ge...

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Detalles Bibliográficos
Autores principales: Guan, Dongyin, Bae, Hosung, Zhou, Dishu, Chen, Ying, Jiang, Chunjie, La, Cam Mong, Xiao, Yang, Zhu, Kun, Hu, Wenxiang, Trinh, Trang Minh, Liu, Panpan, Xiong, Ying, Cai, Bishuang, Jang, Cholsoon, Lazar, Mitchell A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104893/
https://www.ncbi.nlm.nih.gov/pubmed/37066875
http://dx.doi.org/10.1172/JCI163018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104893/
https://www.ncbi.nlm.nih.gov/pubmed/37066875
http://dx.doi.org/10.1172/JCI163018

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