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Kidney glycolysis serves as a mammalian phosphate sensor that maintains phosphate homeostasis

How phosphate levels are detected in mammals is unknown. The bone-derived hormone fibroblast growth factor 23 (FGF23) lowers blood phosphate levels by reducing kidney phosphate reabsorption and 1,25(OH)(2)D production, but phosphate does not directly stimulate bone FGF23 expression. Using PET scanni...

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Detalles Bibliográficos
Autores principales: Zhou, Wen, Simic, Petra, Zhou, Iris Y., Caravan, Peter, Vela Parada, Xavier, Wen, Donghai, Washington, Onica L., Shvedova, Maria, Pierce, Kerry A., Clish, Clary B., Mannstadt, Michael, Kobayashi, Tatsuya, Wein, Marc N., Jüppner, Harald, Rhee, Eugene P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104895/
https://www.ncbi.nlm.nih.gov/pubmed/36821389
http://dx.doi.org/10.1172/JCI164610