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Kidney glycolysis serves as a mammalian phosphate sensor that maintains phosphate homeostasis
How phosphate levels are detected in mammals is unknown. The bone-derived hormone fibroblast growth factor 23 (FGF23) lowers blood phosphate levels by reducing kidney phosphate reabsorption and 1,25(OH)(2)D production, but phosphate does not directly stimulate bone FGF23 expression. Using PET scanni...
Autores principales: | Zhou, Wen, Simic, Petra, Zhou, Iris Y., Caravan, Peter, Vela Parada, Xavier, Wen, Donghai, Washington, Onica L., Shvedova, Maria, Pierce, Kerry A., Clish, Clary B., Mannstadt, Michael, Kobayashi, Tatsuya, Wein, Marc N., Jüppner, Harald, Rhee, Eugene P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104895/ https://www.ncbi.nlm.nih.gov/pubmed/36821389 http://dx.doi.org/10.1172/JCI164610 |
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