Monoclonal antibody Y01 prevents tauopathy progression induced by lysine 280–acetylated tau in cell and mouse models

The spatiotemporal pattern of the spread of pathologically modified tau through brain regions in Alzheimer’s disease (AD) can be explained by prion-like cell-to-cell seeding and propagation of misfolded tau aggregates. Hence, to develop targeted therapeutic antibodies, it is important to identify th...

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Detalles Bibliográficos
Autores principales: Song, Ha-Lim, Kim, Na-Young, Park, Jaewan, Kim, Meong Il, Jeon, Yu-Na, Lee, Se-Jong, Cho, Kwangmin, Shim, Young-Lim, Lee, Kyoung-Hye, Mun, Yeon-Seon, Song, Jung-A, Kim, Min-Seok, Pack, Chan-Gi, Jung, Minkyo, Jang, Hyemin, Na, Duk L., Hong, Minsun, Kim, Dong-Hou, Yoon, Seung-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104896/
https://www.ncbi.nlm.nih.gov/pubmed/36917188
http://dx.doi.org/10.1172/JCI156537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104896/
https://www.ncbi.nlm.nih.gov/pubmed/36917188
http://dx.doi.org/10.1172/JCI156537

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