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Callus γδ T cells and microbe-induced intestinal Th17 cells improve fracture healing in mice

IL-17A (IL-17), a driver of the inflammatory phase of fracture repair, is produced locally by several cell lineages including γδ T cells and Th17 cells. However, the origin of these T cells and their relevance for fracture repair are unknown. Here, we show that fractures rapidly expanded callus γδ T...

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Detalles Bibliográficos
Autores principales: Dar, Hamid Y., Perrien, Daniel S., Pal, Subhashis, Stoica, Andreea, Uppuganti, Sasidhar, Nyman, Jeffry S., Jones, Rheinallt M., Weitzmann, M. Neale, Pacifici, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104897/
https://www.ncbi.nlm.nih.gov/pubmed/36881482
http://dx.doi.org/10.1172/JCI166577