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Callus γδ T cells and microbe-induced intestinal Th17 cells improve fracture healing in mice
IL-17A (IL-17), a driver of the inflammatory phase of fracture repair, is produced locally by several cell lineages including γδ T cells and Th17 cells. However, the origin of these T cells and their relevance for fracture repair are unknown. Here, we show that fractures rapidly expanded callus γδ T...
Autores principales: | Dar, Hamid Y., Perrien, Daniel S., Pal, Subhashis, Stoica, Andreea, Uppuganti, Sasidhar, Nyman, Jeffry S., Jones, Rheinallt M., Weitzmann, M. Neale, Pacifici, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104897/ https://www.ncbi.nlm.nih.gov/pubmed/36881482 http://dx.doi.org/10.1172/JCI166577 |
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