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In situ expansion and reprogramming of Kupffer cells elicit potent tumoricidal immunity against liver metastasis

Liver metastasis represents one of the most frequent malignant diseases with no effective treatment. Functional reprogramming of Kupffer cells (KCs), the largest population of hepatic macrophages, holds promise for treating liver cancer, but remains seldom exploited. Taking advantage of the superior...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Zhou, Xia, Yao, Qi, Chen, Chen, Zhang, Qing, Ding, Keshuo, Li, Lu, Zeng, Zhutian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104906/
https://www.ncbi.nlm.nih.gov/pubmed/36821387
http://dx.doi.org/10.1172/JCI157937