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In situ expansion and reprogramming of Kupffer cells elicit potent tumoricidal immunity against liver metastasis
Liver metastasis represents one of the most frequent malignant diseases with no effective treatment. Functional reprogramming of Kupffer cells (KCs), the largest population of hepatic macrophages, holds promise for treating liver cancer, but remains seldom exploited. Taking advantage of the superior...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104906/ https://www.ncbi.nlm.nih.gov/pubmed/36821387 http://dx.doi.org/10.1172/JCI157937 |