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Mechanisms of chromosomal instability (CIN) tolerance in aggressive tumors: surviving the genomic chaos

Chromosomal instability (CIN) is a pervasive feature of human cancers involved in tumor initiation and progression and which is found elevated in metastatic stages. CIN can provide survival and adaptation advantages to human cancers. However, too much of a good thing may come at a high cost for tumo...

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Detalles Bibliográficos
Autores principales: Dhital, Brittiny, Rodriguez-Bravo, Veronica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104937/
https://www.ncbi.nlm.nih.gov/pubmed/37058263
http://dx.doi.org/10.1007/s10577-023-09724-w