CD95/Fas ligand mRNA is toxic to cells through more than one mechanism

CD95/Fas ligand (CD95L) induces apoptosis through protein binding to the CD95 receptor. However, CD95L mRNA also induces toxicity in the absence of CD95 through induction of DISE (Death Induced by Survival Gene Elimination), a form of cell death mediated by RNA interference (RNAi). We now report tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Haluck-Kangas, Ashley, Fink, Madelaine, Bartom, Elizabeth T., Peter, Marcus E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105004/
https://www.ncbi.nlm.nih.gov/pubmed/37059938
http://dx.doi.org/10.1186/s43556-023-00119-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105004/
https://www.ncbi.nlm.nih.gov/pubmed/37059938
http://dx.doi.org/10.1186/s43556-023-00119-1

Ejemplares similares