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Striatal Dopamine Loss in Early Parkinson's Disease: Systematic Review and Novel Analysis of Dopamine Transporter Imaging

BACKGROUND: Neuropathological studies, based on small samples, suggest that symptoms of Parkinson's disease (PD) emerge when dopamine/nigrostriatal loss is around 50–80%. Functional neuroimaging can be applied in larger numbers during life, which allows analysis of the extent of dopamine loss m...

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Detalles Bibliográficos
Autores principales: Heng, Nicholas, Malek, Naveed, Lawton, Michael A., Nodehi, Anahita, Pitz, Vanessa, Grosset, Katherine A., Ben‐Shlomo, Yoav, Grosset, Donald G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105104/
https://www.ncbi.nlm.nih.gov/pubmed/37070042
http://dx.doi.org/10.1002/mdc3.13687