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Striatal Dopamine Loss in Early Parkinson's Disease: Systematic Review and Novel Analysis of Dopamine Transporter Imaging
BACKGROUND: Neuropathological studies, based on small samples, suggest that symptoms of Parkinson's disease (PD) emerge when dopamine/nigrostriatal loss is around 50–80%. Functional neuroimaging can be applied in larger numbers during life, which allows analysis of the extent of dopamine loss m...
Autores principales: | Heng, Nicholas, Malek, Naveed, Lawton, Michael A., Nodehi, Anahita, Pitz, Vanessa, Grosset, Katherine A., Ben‐Shlomo, Yoav, Grosset, Donald G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105104/ https://www.ncbi.nlm.nih.gov/pubmed/37070042 http://dx.doi.org/10.1002/mdc3.13687 |
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