Cognitive decline in diabetic mice predisposed to Alzheimer’s disease is greater than in wild type

In this work, we tested the hypothesis that the development of dementia in individuals with type 2 diabetes (T2DM) requires a genetic background of predisposition to neurodegenerative disease. As a proof of concept, we induced T2DM in middle-aged hAPP NL/F mice, a preclinical model of Alzheimer’s di...

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Detalles Bibliográficos
Autores principales: Carús-Cadavieco, Marta, Berenguer López, Inés, Montoro Canelo, Alba, Serrano-Lope, Miguel A, González-de la Fuente, Sandra, Aguado, Begoña, Fernández-Rodrigo, Alba, Saido, Takaomi C, Frank García, Ana, Venero, César, Esteban, José A, Guix, Francesc, Dotti, Carlos G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105330/
https://www.ncbi.nlm.nih.gov/pubmed/37059474
http://dx.doi.org/10.26508/lsa.202201789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105330/
https://www.ncbi.nlm.nih.gov/pubmed/37059474
http://dx.doi.org/10.26508/lsa.202201789

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