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Methadone rotation versus other opioid rotation for refractory cancer induced bone pain: protocol of an exploratory randomised controlled open-label study

BACKGROUND: A third of patients with advanced cancer and bone metastasis suffer from cancer induced bone pain (CIBP), impeding quality of life, psychological distress, depression and anxiety. This study will evaluate the impact of an opioid rotation, comparing methadone rotation with other opioid ro...

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Detalles Bibliográficos
Autores principales: Michael, Natasha, Sulistio, Merlina, Wojnar, Robert, Gorelik, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105403/
https://www.ncbi.nlm.nih.gov/pubmed/37059995
http://dx.doi.org/10.1186/s12904-023-01160-1