ASAP2 interrupts c-MET-CIN85 interaction to sustain HGF/c-MET-induced malignant potentials in hepatocellular carcinoma

BACKGROUND: Sustained activation of hepatocyte growth factor (HGF)/c-MET signaling is a major driver of hepatocellular carcinoma (HCC) progression, but underlying mechanism is unclear. ArfGAP With SH3 Domain, Ankyrin Repeat And PH Domain 2 (ASAP2) can reportedly activate GTPases and promote receptor...

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Detalles Bibliográficos
Autores principales: Ma, Xiao-Lu, Nie, Yan-Yan, Xie, Su-Hong, Zheng, Hui, Tong, Ying, Wang, Yan-Chun, Yan, Tian-Qing, Meng, Xin, Cao, Jia-Zhen, Tang, Wei-Guo, Guo, Lin, Lu, Ren-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105420/
https://www.ncbi.nlm.nih.gov/pubmed/37061723
http://dx.doi.org/10.1186/s40164-023-00393-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105420/
https://www.ncbi.nlm.nih.gov/pubmed/37061723
http://dx.doi.org/10.1186/s40164-023-00393-3

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