Development of a Single-Chain Fragment Variable that Binds to the SARS-CoV-2 Spike Protein Produced by Genetically Modified Lactic Acid Bacteria

SARS-CoV-2 enters cells via binding of the surface-exposed spike protein RBD to host cell ACE2 receptors. Therefore, in this study, we designed a scFv (single-chain fragment variable) based on the amino acid sequence of CC12.1, a neutralizing antibody found in the serum of patients with COVID-19. sc...

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Detalles Bibliográficos
Autores principales: Oshima, Suzuka, Namai, Fu, Sato, Takashi, Shimosato, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105526/
https://www.ncbi.nlm.nih.gov/pubmed/37060514
http://dx.doi.org/10.1007/s12033-023-00741-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105526/
https://www.ncbi.nlm.nih.gov/pubmed/37060514
http://dx.doi.org/10.1007/s12033-023-00741-y

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