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PI3K/AKT/mTOR pathway and its related molecules participate in PROK1 silence-induced anti-tumor effects on pancreatic cancer

The PI3K/AKT/mTOR (phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin) pathway can be initiated by PROK1 (prokineticin 1), but its effect and mechanism of action in pancreatic carcinoma (PC) are not fully understood. In this study, we elucidated the roles of PROK1 and its r...

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Detalles Bibliográficos
Autores principales: Wang, Feng, Yan, Xiaogang, Hua, Yongqiang, Song, Jianjun, Liu, Di, Yang, Chun, Peng, Fei, Kang, Fuping, Hui, Yongfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105552/
https://www.ncbi.nlm.nih.gov/pubmed/37070074
http://dx.doi.org/10.1515/biol-2022-0538