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Transcriptomics reveals the effects of NTRK1 on endoplasmic reticulum stress response-associated genes in human neuronal cell lines

BACKGROUND: NTRK1 gene, encoding TrkA, is essential for the nervous system and drives a variety of biological processes, including pain. Given the unsatisfied analgesic effects of some new drugs targeting NTRK1 in clinic, a deeper understanding for the mechanism of NTRK1 in neurons is crucial. METHO...

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Detalles Bibliográficos
Autores principales: Jiao, Bo, Zhang, Mi, Zhang, Caixia, Cao, Xueqin, Liu, Baowen, Li, Ningbo, Sun, Jiaoli, Zhang, Xianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105561/
https://www.ncbi.nlm.nih.gov/pubmed/37070091
http://dx.doi.org/10.7717/peerj.15219