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Structural Modelling of Platelet Activating Factor Acetyl Hydrolase in Leishmania donovani, Trypanosoma cruzi, and Trypanosoma brucei: Implications on Therapeutics for Leishmaniasis, Chagas Disease, and Sleeping Sickness

PURPOSE: Leishmaniasis, Chagas disease, and sleeping sickness are caused by protozoa Leishmania donovani, Trypanosoma cruzi, and Trypanosoma brucei, respectively. Platelet activating factor acetyl hydrolase (PAF-AH) is an inflammatory protein implicated in pathogenesis of these three infections, the...

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Detalles Bibliográficos
Autores principales: Goswami, Arunima, Koley, Tirthankar, Rajan, Madhan Vishal, Madhuri, Pathak, Upadhyay, Neelam, Das, Uddipan, Kumar, Manoj, Ethayathulla, Abdul Samath, Hariprasad, Gururao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105589/
https://www.ncbi.nlm.nih.gov/pubmed/37070125
http://dx.doi.org/10.2147/IDR.S403411