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sgRNAs: A SARS-CoV-2 emerging issue

Like for other coronaviruses, SARS-CoV-2 gene expression strategy is based on the synthesis of a nested set of subgenomic mRNA species (sgRNAs). These sgRNA are synthesized using a “discontinuous transcription” mechanism that relies on template switching at Transcription Regulatory Sequences (TRS)....

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Detalles Bibliográficos
Autores principales: Mori, Antonio, Lavezzari, Denise, Pomari, Elena, Deiana, Michela, Piubelli, Chiara, Capobianchi, Maria Rosaria, Castilletti, Concetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105645/
https://www.ncbi.nlm.nih.gov/pubmed/37519862
http://dx.doi.org/10.1016/j.amolm.2023.100008