Pendrin abundance, subcellular distribution, and function are unaffected by either αENaC gene ablation or by increasing ENaC channel activity

The intercalated cell Cl(−)/HCO(3)(−) exchanger, pendrin, modulates ENaC subunit abundance and function. Whether ENaC modulates pendrin abundance and function is however unknown. Because αENaC mRNA has been detected in pendrin-positive intercalated cells, we hypothesized that ENaC, or more specifica...

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Detalles Bibliográficos
Autores principales: Loffing, Johannes, Pech, Vladimir, Loffing-Cueni, Dominique, Abood, Delaney C., Kim, Young Hee, Chen, Chao, Pham, Truyen D., Verlander, Jill W., Wall, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Ion Channels, Receptors and Transporters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105674/
https://www.ncbi.nlm.nih.gov/pubmed/36977894
http://dx.doi.org/10.1007/s00424-023-02797-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105674/
https://www.ncbi.nlm.nih.gov/pubmed/36977894
http://dx.doi.org/10.1007/s00424-023-02797-w

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