Transcriptomics of Hirschsprung disease patient-derived enteric neural crest cells reveals a role for oxidative phosphorylation

Hirschsprung disease is characterized by the absence of enteric neurons caused by the defects of enteric neural crest cells, leading to intestinal obstruction. Here, using induced pluripotent stem cell-based models of Hirschsprung and single-cell transcriptomic analysis, we identify a gene set of 11...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Zhixin, Lui, Kathy Nga-Chu, Lau, Sin-Ting, Lai, Frank Pui-Ling, Li, Peng, Chung, Patrick Ho-Yu, Wong, Kenneth Kak-Yuen, Tam, Paul Kwong-Hing, Garica-Barcelo, Maria-Mercedes, Hui, Chi-Chung, Sham, Pak Chung, Ngan, Elly Sau-Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105741/
https://www.ncbi.nlm.nih.gov/pubmed/37061531
http://dx.doi.org/10.1038/s41467-023-37928-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105741/
https://www.ncbi.nlm.nih.gov/pubmed/37061531
http://dx.doi.org/10.1038/s41467-023-37928-5

Ejemplares similares