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A proof-of-concept assay for quantitative and optical assessment of drug-induced toxicity in renal organoids

Kidneys are complex organs, and reproducing their function and physiology in a laboratory setting remains difficult. During drug development, potential compounds may exhibit unexpected nephrotoxic effects, which imposes a significant financial burden on pharmaceutical companies. As a result, there i...

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Detalles Bibliográficos
Autores principales: Dilz, Jasmin, Auge, Isabel, Groeneveld, Kathrin, Reuter, Stefanie, Mrowka, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105743/
https://www.ncbi.nlm.nih.gov/pubmed/37061575
http://dx.doi.org/10.1038/s41598-023-33110-5