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A proof-of-concept assay for quantitative and optical assessment of drug-induced toxicity in renal organoids
Kidneys are complex organs, and reproducing their function and physiology in a laboratory setting remains difficult. During drug development, potential compounds may exhibit unexpected nephrotoxic effects, which imposes a significant financial burden on pharmaceutical companies. As a result, there i...
Autores principales: | Dilz, Jasmin, Auge, Isabel, Groeneveld, Kathrin, Reuter, Stefanie, Mrowka, Ralf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105743/ https://www.ncbi.nlm.nih.gov/pubmed/37061575 http://dx.doi.org/10.1038/s41598-023-33110-5 |
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