Structural and immunological differences in Plasmodium falciparum sexual stage transmission-blocking vaccines comprised of Pfs25-EPA nanoparticles

Development of a malaria vaccine that blocks transmission of different parasite stages to humans and mosquitoes is considered critical for elimination efforts. A vaccine using Pfs25, a protein on the surface of zygotes and ookinetes, is under investigation as a transmission-blocking vaccine (TBV) th...

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Detalles Bibliográficos
Autores principales: MacDonald, Nicholas J., Singh, Kavita, Reiter, Karine, Nguyen, Vu, Shimp, Richard, Gittis, Apostolos G., Chen, Beth, Burkhardt, Martin, Zhang, Baoshan, Wang, Zhixiong, Herrera, Raul, Moler, Mackenzie, Lee, Duck-Yeon, Orr-Gonzalez, Sachy, Herrod, Jessica, Lambert, Lynn E., Rausch, Kelly M., Muratova, Olga, Jones, David S., Wu, Yimin, Jin, Albert J., Garboczi, David N., Duffy, Patrick E., Narum, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105769/
https://www.ncbi.nlm.nih.gov/pubmed/37061547
http://dx.doi.org/10.1038/s41541-023-00655-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105769/
https://www.ncbi.nlm.nih.gov/pubmed/37061547
http://dx.doi.org/10.1038/s41541-023-00655-5

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