SIAH1 ubiquitination-modified HMGCR inhibits lung cancer progression and promotes drug sensitivity through cholesterol synthesis

BACKGROUNDS: Lung cancer is one of the most frequently diagnosed cancers and the leading cause of cancer-related deaths worldwide. Deep understanding of chemoresistance will lead to remarkable progress in lung cancer treatment strategy. Cholesterol accumulation was associated with cisplatin resistan...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Hongmei, Wu, Hongge, Cheng, Jing, Xiong, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105949/
https://www.ncbi.nlm.nih.gov/pubmed/37062828
http://dx.doi.org/10.1186/s12935-023-02914-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105949/
https://www.ncbi.nlm.nih.gov/pubmed/37062828
http://dx.doi.org/10.1186/s12935-023-02914-w

Ejemplares similares