PCK1 activates oncogenic autophagy via down-regulation Serine phosphorylation of UBAP2L and antagonizes colorectal cancer growth

Phosphoenolpyruvate carboxykinase 1 (PCK1) is the rate-limiting enzyme in gluconeogenesis. PCK1 is considered an anti-oncogene in several human cancers. In this study, we aimed to determine the functions of PCK1 in colorectal cancer (CRC). PCK1 expression in CRC tissues was tested by western blot an...

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Detalles Bibliográficos
Autores principales: Zhang, Xiangyan, Tao, Geru, Jiang, Jie, Qu, Tingting, Zhao, Shuchao, Xu, Ping, Zhao, Ya’nan, Xing, Xiaoming, Qin, Shucun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105959/
https://www.ncbi.nlm.nih.gov/pubmed/37062825
http://dx.doi.org/10.1186/s12935-023-02894-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105959/
https://www.ncbi.nlm.nih.gov/pubmed/37062825
http://dx.doi.org/10.1186/s12935-023-02894-x

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