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Expansion and characterization of human limbus-derived stromal/mesenchymal stem cells in xeno-free medium for therapeutic applications

BACKGROUND: Mesenchymal stem cells (MSCs) have been proven to prevent and clear corneal scarring and limbal stem cell deficiency. However, using animal-derived serum in a culture medium raises the ethical and regulatory bar. This study aims to expand and characterize human limbus-derived stromal/mes...

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Detalles Bibliográficos
Autores principales: Sahoo, Abhishek, Damala, Mukesh, Jaffet, Jilu, Prasad, Deeksha, Basu, Sayan, Singh, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105964/
https://www.ncbi.nlm.nih.gov/pubmed/37061739
http://dx.doi.org/10.1186/s13287-023-03299-3