Cargando…

Brevilin A is a potent anti-metastatic CRC agent that targets the VEGF-IL6-STAT3 axis in the HSCs-CRC interplay

BACKGROUND: More than half of the colorectal cancer (CRC) patients will develop liver metastasis that underlies the cancer mortality. In the hepatic tumor microenvironment, the interplay between CRC cells and hepatic stellate cells (HSCs), and the activation of HSCs to become carcinoma-associated fi...

Descripción completa

Detalles Bibliográficos
Autores principales: Fan, Xueying, Meng, Mingjing, Li, Baoting, Chen, Hui, Tan, Jincheng, Xu, Keyang, Xiao, Shilin, Kwan, Hiu-Yee, Liu, Zhongqiu, Su, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105967/
https://www.ncbi.nlm.nih.gov/pubmed/37062842
http://dx.doi.org/10.1186/s12967-023-04087-6