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Somatic and terminal CB1 receptors are differentially coupled to voltage-gated sodium channels in neocortical neurons

Endogenous cannabinoid signaling is vital for important brain functions, and the same pathways can be modified pharmacologically to treat pain, epilepsy, and posttraumatic stress disorder. Endocannabinoid-mediated changes to excitability are predominantly attributed to 2-arachidonoylglycerol (2-AG)...

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Detalles Bibliográficos
Autores principales: Steiger, Luke J., Tsintsadze, Timur, Mattheisen, Glynis B., Smith, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106091/
https://www.ncbi.nlm.nih.gov/pubmed/36933217
http://dx.doi.org/10.1016/j.celrep.2023.112247