Cargando…
Somatic and terminal CB1 receptors are differentially coupled to voltage-gated sodium channels in neocortical neurons
Endogenous cannabinoid signaling is vital for important brain functions, and the same pathways can be modified pharmacologically to treat pain, epilepsy, and posttraumatic stress disorder. Endocannabinoid-mediated changes to excitability are predominantly attributed to 2-arachidonoylglycerol (2-AG)...
Autores principales: | Steiger, Luke J., Tsintsadze, Timur, Mattheisen, Glynis B., Smith, Stephen M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106091/ https://www.ncbi.nlm.nih.gov/pubmed/36933217 http://dx.doi.org/10.1016/j.celrep.2023.112247 |
Ejemplares similares
-
Strong G-Protein-Mediated Inhibition of Sodium Channels
por: Mattheisen, Glynis B., et al.
Publicado: (2018) -
Enhanced excitability of cortical neurons in low-divalent solutions is primarily mediated by altered voltage-dependence of voltage-gated sodium channels
por: Martiszus, Briana J, et al.
Publicado: (2021) -
Voltage-Gated Sodium Channels in Neocortical Pyramidal Neurons Display Cole-Moore Activation Kinetics
por: Almog, Mara, et al.
Publicado: (2018) -
Biophysical Properties of Somatic and Axonal Voltage-Gated Sodium Channels in Midbrain Dopaminergic Neurons
por: Yang, Jun, et al.
Publicado: (2019) -
Fenestropathy of Voltage-Gated Sodium Channels
por: Gamal El-Din, Tamer M., et al.
Publicado: (2022)